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Absolute Basophil Count, Automated (Cord Blood)

Complete Blood Count

BASO Abs (Cord)Basophils Absolute Count, Cord Blood

Review status

Currently under review

Pending specialist review and validation.

What it shows

This test measures the absolute number of basophils in a newborn’s cord blood using an automated analyzer. Basophils are a type of white blood cell involved in immune responses, particularly in allergic reactions and inflammation. The result reflects how many basophils are present, not just the percentage, which helps provide a clearer picture of the baby’s immune cell profile at birth.

Cord blood is collected from the umbilical cord immediately after delivery. Because it is taken at birth, the result offers a snapshot of the baby’s white blood cell makeup at that moment, before outside exposures after delivery can influence the values.

Why it matters

Clinicians use this test as part of a complete blood count with differential to help evaluate a newborn’s overall health. It can support the assessment of possible infection, inflammation, allergic tendencies, or certain blood conditions. While basophil changes are less common in newborns than other white cell changes, the absolute count can add context to other findings.

Results are interpreted together with the total white blood cell count, other differential cell counts, the baby’s exam, and maternal and delivery history. The test may be ordered for babies who appear unwell, when there are concerns about infection or inflammation, or to establish a baseline in specific clinical situations.

Understanding your results

Most results fall within an expected range for cord blood. A higher or lower basophil count on its own rarely provides a diagnosis. Your care team will interpret the result alongside other blood counts and your baby’s clinical picture. Mild deviations can occur for many benign reasons, including normal newborn transition.

If results are unexpected, your clinician may repeat the test after a short interval or order additional studies. Any follow up will consider maternal health, delivery factors, and the presence of symptoms in your baby. Ask your care team how this result fits with the rest of the evaluation and whether any further testing is needed.

Reference ranges

00.22 10⁹/L
All sexes
0 days – 150 years

Reference intervals vary by laboratory, analyzer, methodology, population, and units. The ranges shown here are for education only. Always interpret your results against the reference interval printed on your own lab report.

Factors that could impact Absolute Basophil Count, Automated (Cord Blood)

  • Timing of cord clamping and sampling

    The interval between delivery, cord clamping, and sample collection can influence white blood cell distribution, including basophils, due to physiologic shifts that occur immediately after birth.

  • Specimen handling and anticoagulant

    Improper mixing, clotting, or delays in analysis can alter automated cell counts. Using the correct tube, adequate mixing, and prompt processing help ensure accurate basophil measurements.

  • Maternal medications and exposures

    Corticosteroids and other medications taken by the mother near delivery can affect neonatal white blood cell counts. Share details about maternal therapies, supplements, and recent treatments.

  • Infection, inflammation, and allergic activity

    Basophils participate in inflammatory and allergic responses. Infections, parasitic exposures, or inflammatory conditions can influence basophil counts, though such patterns in newborns are often subtle.

  • Prematurity and perinatal stress

    Preterm birth, labor stress, and conditions like growth restriction can shift white blood cell populations. These factors are considered when interpreting a newborn’s basophil count.

  • Analyzer and differential methodology

    Automated analyzers use specific algorithms to classify cells. Instrument differences, calibration, and confirmatory smear review policies can affect reported basophil counts.

2026

References

  1. McGill University Health Centre. (2018, May 03). Abs. Basophil Automated Cord Blood (Task CD 21332165). Laboratory reference ranges.
  2. Clinical and Laboratory Standards Institute. (2010). Defining, establishing, and verifying reference intervals in the clinical laboratory (3rd ed., CLSI document EP28-A3c).
  3. Bain, B. J., Bates, I., & Laffan, M. A. (2021). Dacie and Lewis practical haematology (12th ed.). Elsevier.