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Aldosterone, blood (0 minute baseline)

Endocrine & Reproductive

AldoPlasma aldosterone

Review status

Currently under review

Pending specialist review and validation.

What it shows

This test measures the amount of aldosterone in your blood at a baseline time point, sometimes labeled 0 minutes. Aldosterone is a hormone made by your adrenal glands that helps your body control salt, water, and potassium balance, which influences blood pressure and fluid status.

It is often assessed alongside renin or as part of a series of timed samples to understand how your adrenal system is responding under specific conditions such as posture or salt intake. Your clinician uses this baseline value to compare with other measurements and clinical findings.

Why it matters

Measuring aldosterone can help find the cause of high blood pressure that is difficult to control, low potassium, or symptoms that suggest your body is holding too much salt or water. It is a key test when your clinician is considering primary aldosteronism, a condition where the adrenal glands make too much aldosterone.

The result can also provide clues about adrenal insufficiency or problems with the kidneys or blood flow to the kidneys. Understanding your aldosterone level helps guide next steps, which may include medication adjustments, confirmatory testing, or imaging, depending on your overall health and history.

Understanding your results

Your result will be interpreted in the context of how and when the sample was collected, your salt intake, your posture before the draw, and any medicines you take. Different laboratories can use different methods, so your healthcare professional will compare your result to the reference interval used by the testing lab and to your clinical picture.

If your level is higher or lower than expected, your clinician may repeat the test under controlled conditions, review medications that can affect aldosterone, and order related tests such as renin or confirmatory suppression or stimulation tests. In some cases, further evaluation with imaging or specialty referral is considered. Do not change or stop medications without medical guidance.

Reference ranges

111860 pmol/L
All sexes
0 days – 150 years

Reference intervals vary by laboratory, analyzer, methodology, population, and units. The ranges shown here are for education only. Always interpret your results against the reference interval printed on your own lab report.

Factors that could impact Aldosterone, blood (0 minute baseline)

  • Posture and timing

    Aldosterone varies with posture and time of day. Whether you are lying down, seated, or upright before the blood draw and how long you were in that position can affect the result.

  • Salt and fluid intake

    High or low dietary sodium, dehydration, or recent changes in fluid intake can alter aldosterone. Your clinician may ask you to follow specific instructions about salt or hydration before testing.

  • Medications

    Drugs such as diuretics, ACE inhibitors, ARBs, beta blockers, mineralocorticoid receptor antagonists, oral contraceptives, and licorice products can affect aldosterone. Provide a full medication list.

  • Related hormone testing

    Aldosterone is often interpreted with renin to understand the renin-angiotensin-aldosterone system. An isolated value without renin may be harder to interpret.

  • Kidney and adrenal health

    Conditions affecting the kidneys or adrenal glands, including adrenal growths or impaired kidney blood flow, can change aldosterone levels independent of medications.

  • Pregnancy and hormones

    Pregnancy and estrogen exposure can raise aldosterone. Results in these settings are interpreted with caution and may require specialized reference information.

2026

References

  1. McGill University Health Centre. (2014, June 11). Aldosterone 0m (Task CD 713046). Laboratory reference ranges.
  2. Funder, J. W., Carey, R. M., Mantero, F., Murad, M. H., Reincke, M., Shibata, H., Stowasser, M., & Young, W. F. (2016). The management of primary aldosteronism: Case detection, diagnosis, and treatment: An Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism, 101(5), 1889–1916. External link