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Anti-Mullerian Hormone

Endocrine & Reproductive

AMHMISMüllerian Inhibiting HormoneMullerian Inhibiting Substance

Review status

Currently under review

Pending specialist review and validation.

What it shows

Anti-Mullerian Hormone is a protein made mainly by cells in the ovaries in women and by Sertoli cells in the testes in males. In adults with ovaries, AMH reflects the number of small developing follicles, often called ovarian reserve. In infants and children, especially males, AMH helps assess testicular presence and function.

AMH is measured in a blood sample. Levels tend to be relatively stable across the menstrual cycle compared with many other hormones, and they are influenced by age, reproductive biology, and certain medical conditions. Your clinician interprets AMH alongside your history and other tests.

Why it matters

For people with ovaries, AMH helps estimate ovarian reserve, guide fertility counseling, and inform decisions such as timing or dosing for assisted reproductive treatments. It can also provide context when periods are irregular and may support evaluation for conditions that affect ovarian function.

In infants, children, and adults with testes, AMH can help determine whether testicular tissue is present and functioning, which is useful in evaluating undescended testes and some differences of sex development. AMH is not a standalone measure of fertility potential or egg quality; it is one piece of a broader clinical picture that includes age, ultrasound findings, and other lab tests.

Understanding your results

Your AMH result is interpreted using age- and sex-specific expectations, your medical history, and your goals, such as family planning. In people with ovaries, higher or lower values can suggest differences in the remaining pool of follicles, but AMH does not predict whether you will conceive or the health of future pregnancies. In people with testes, results help assess whether testes are present and producing hormones appropriate for age.

If your result is unexpected, your clinician may review medications, supplements, and timing, consider repeating the test, or order related tests like follicle-stimulating hormone, antral follicle count by ultrasound, estradiol, or semen analysis. Because assays differ between laboratories, trends are best followed using the same method when possible.

Reference ranges

0 – 3.39 ng/mL
Female
0 days – 2 months
15.11 – 266.59 ng/mL
Male
0 days – 2 months
0 – 4.7 ng/mL
Female
2 months – 2 years
14 – 466 ng/mL
Male
2 months – 2 years
0 – 8.8 ng/mL
Female
2 years – 12 years
7.4 – 243 ng/mL
Male
2 years – 12 years
0.9 – 9.5 ng/mL
Female
12 years – 18 years
0.7 – 19 ng/mL
Male
12 years – 18 years
0.96 – 13.34 ng/mL
Female
18 years – 25 years
0.73 – 16.05 ng/mL
Male
18 years – 150 years
0.17 – 7.37 ng/mL
Female
25 years – 30 years
0.07 – 7.35 ng/mL
Female
30 years – 35 years
0.03 – 7.15 ng/mL
Female
35 years – 40 years
0 – 3.27 ng/mL
Female
40 years – 45 years
0 – 1.15 ng/mL
Female
45 years – 150 years

Reference intervals vary by laboratory, analyzer, methodology, population, and units. The ranges shown here are for education only. Always interpret your results against the reference interval printed on your own lab report.

Factors that could impact Anti-Mullerian Hormone

  • Age and biological sex

    AMH naturally changes with age and differs between people with ovaries and those with testes. Interpretation always accounts for age and sex, especially in children and around reproductive milestones.

  • Hormonal contraceptives and pregnancy

    Combined oral contraceptives and pregnancy can lower measured AMH temporarily. Levels may rebound after stopping contraception or after pregnancy, so timing can affect interpretation.

  • Ovarian or testicular conditions

    Polycystic ovary syndrome, prior ovarian surgery, chemotherapy, radiation, endometriosis, and ovarian cysts can influence AMH. In males, anorchia or undescended testes can be reflected in AMH patterns.

  • Assay differences and supplements

    Different laboratory methods can yield slightly different results. High-dose biotin and heterophile antibodies can interfere with some immunoassays, so tell your clinician about supplements before testing.

  • Sample handling and timing

    Hemolysis, delayed processing, or extreme storage conditions can affect measurements. Although AMH varies less by time of day, using the same lab and conditions helps with reliable comparisons.

2026

References

  1. McGill University Health Centre. (2017, November 22). Anti-Mullerian Hormone (Task CD 10657269). Laboratory reference ranges.
  2. McGill University Health Centre. (2021, June 10). Anti-Mullerian Hormone (Task CD 10657269). Laboratory reference ranges.
  3. Practice Committee of the American Society for Reproductive Medicine. (2020). Testing and interpreting measures of ovarian reserve: A committee opinion. Fertility and Sterility, 114(6), 1151-1157. External link
  4. European Society of Human Reproduction and Embryology. (2019). Ovarian stimulation for IVF/ICSI: ESHRE guideline update 2019. External link