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Blood Gas Lactate

Electrolytes

LacLactate (blood gas)

Review status

Currently under review

Pending specialist review and validation.

What it shows

This test measures the amount of lactate in your blood using a blood gas analyzer. Lactate is a substance your body makes when cells use glucose for energy, especially when oxygen delivery is limited or your body is under stress.

It is typically performed on arterial or venous whole blood collected in a syringe and analyzed promptly. Because lactate can change quickly, the test is often used in emergency and critical care settings to give real-time information about your status.

Why it matters

Lactate helps your care team judge how well your tissues are receiving oxygen and how your body is coping with illness or injury. Higher levels can occur with serious infections, shock, heart or lung problems, severe dehydration, seizures, or after major injuries. Levels can also rise with intense exercise or from some medicines, and may increase when the liver or kidneys have trouble clearing lactate.

Clinicians order this test when you are acutely unwell, to help find the cause of symptoms such as low blood pressure or shortness of breath, to assess response to treatment, and to guide urgent decisions. Tracking lactate over time can help show whether treatment is working and whether blood flow and oxygen delivery are improving.

Understanding your results

Your result is interpreted together with your symptoms, vital signs, and other lab and imaging findings. A higher-than-expected lactate suggests that your body is under stress or that oxygen delivery may be limited, but it does not identify a single cause on its own. Changes over time are often more informative than a single value, and a level that improves with treatment is generally reassuring.

If your level is higher than expected, your clinician may repeat the test, review your medications, check your oxygen status and blood pressure, and evaluate for infection or organ dysfunction. Lower-than-expected values are uncommon and usually not concerning by themselves. Ask your care team what your result means for you and whether any additional testing or treatment is needed.

Reference ranges

02 mmol/L
All sexes
0 days – 150 years

Reference intervals vary by laboratory, analyzer, methodology, population, and units. The ranges shown here are for education only. Always interpret your results against the reference interval printed on your own lab report.

Factors that could impact Blood Gas Lactate

  • Strenuous exercise

    Intense physical activity shortly before sampling can raise lactate for a short period. Resting before the draw helps avoid exercise-related elevations that do not reflect illness.

  • Sample handling and timing

    Prolonged tourniquet time, delayed analysis, or a warm sample can allow cells to keep producing lactate in the tube, leading to falsely high results. Rapid processing minimizes this effect.

  • Medications and substances

    Drugs such as beta-agonists, epinephrine, metformin, linezolid, propofol, and certain antiretrovirals, as well as alcohol, can increase lactate. Tell your clinician what you take.

  • Liver or kidney function

    The liver clears most lactate and the kidneys contribute as well. Reduced function can lead to higher levels even without a new illness causing extra lactate production.

  • Seizures, shivering, or severe pain

    These conditions can drive muscles to produce more lactate for a short time. Levels often fall as the triggering event resolves and treatment begins.

  • Type of blood sample

    Arterial and venous samples can differ slightly, and line draws may be affected by infusions. How and where the sample is taken can influence the result.

2026

References

  1. McGill University Health Centre. (2018, June 13). BG Lactate CL (Task CD 6117173). Laboratory reference ranges.
  2. Evans, L., Rhodes, A., Alhazzani, W., Antonelli, M., Coopersmith, C. M., French, C., ... & Levy, M. M. (2021). Surviving Sepsis Campaign: International guidelines for management of sepsis and septic shock 2021. Intensive Care Medicine, 47, 1181–1247. External link
  3. Kraut, J. A., & Madias, N. E. (2014). Lactic acidosis. New England Journal of Medicine, 371(24), 2309–2319. External link