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Relative neutrophils (cord blood)

Complete Blood Count

NE% cordNeutrophil percentage, cord bloodRelative neutrophils, cord

Review status

Currently under review

Pending specialist review and validation.

What it shows

This test measures the percentage of neutrophils, a type of white blood cell, in a sample of umbilical cord blood collected immediately after birth. Neutrophils are key defenders against bacterial infections, and the result reflects how large a share of all white blood cells are neutrophils at that moment.

It is typically performed as part of a complete blood count with differential for a newborn. Clinicians use it to understand the baby’s immune and inflammatory status at birth, especially if there were concerns during pregnancy or delivery, or if the baby needs closer evaluation for possible infection.

Why it matters

The relative neutrophil percentage can help your baby’s care team evaluate the likelihood of infection or inflammation and guide decisions about monitoring and treatment. A higher or lower proportion of neutrophils can occur with stress around delivery, early infection, or other medical conditions that affect how white blood cells are produced or used.

On its own, this result is not diagnostic. It is interpreted together with your baby’s exam, medical history, and other tests, such as the absolute neutrophil count, the presence of immature white cells, and infection markers. This combined picture helps decide whether simple observation, repeat testing, or antibiotics are appropriate.

Understanding your results

Your baby’s result is interpreted in the context of gestational age, how the delivery went, maternal medications, and when the sample was collected. Newborn white blood cell patterns naturally change around birth, so timing matters for understanding what a result means.

A higher proportion of neutrophils can be seen with infection, inflammation, or physiologic stress. A lower proportion can occur if neutrophils are being used up, if production is temporarily limited, or if other white cell types are relatively increased. If the result raises concern, the team may repeat the test, look at the absolute neutrophil count and immature-to-total ratio, order infection markers, or perform cultures. Your clinician will explain next steps and whether any treatment is needed.

Reference ranges

5160 %
All sexes
0 days – 2 days

Reference intervals vary by laboratory, analyzer, methodology, population, and units. The ranges shown here are for education only. Always interpret your results against the reference interval printed on your own lab report.

Factors that could impact Relative neutrophils (cord blood)

  • Timing of collection

    Neonatal white blood cell patterns shift around birth. Results can differ depending on whether the cord blood was collected immediately or after a delay.

  • Sample handling and quality

    Clotting, dilution, or delayed processing can alter the differential count. Proper mixing and prompt analysis help ensure accurate results.

  • Maternal medications

    Corticosteroids and some stress-related medicines can increase circulating neutrophils. Other drugs may influence bone marrow release or cell distribution.

  • Labor and delivery factors

    Prolonged labor, fever, chorioamnionitis, or operative delivery can affect neonatal stress responses and neutrophil proportions at birth.

  • Gestational age and prematurity

    Preterm infants can have different baseline white blood cell patterns and marrow reserves, which may influence relative neutrophil percentages.

  • Contamination or mixing of blood

    Accidental mixing with maternal blood or fluids from the cord can skew results. Careful collection from the cord vessel reduces this risk.

2026

References

  1. McGill University Health Centre. (2018, May 03). Relative Neutrophil Cord Blood (Task CD 21327847). Laboratory reference ranges.
  2. Puopolo, K. M., Benitz, W. E., Zaoutis, T. E., Committee on Fetus and Newborn, & Committee on Infectious Diseases. (2018). Management of neonates born at ≥35 0/7 weeks' gestation with suspected or proven early-onset bacterial sepsis. Pediatrics, 142(6), e20182894.
  3. National Institute for Health and Care Excellence. (2021). Neonatal infection: antibiotics for prevention and treatment (NG195).