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Electrolytes
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The sodium test measures the concentration of sodium in your blood. Sodium is a key electrolyte that helps regulate fluid balance, blood pressure, and how nerves and muscles function.
This test uses a blood sample taken from a vein and is commonly performed with other electrolytes and kidney function tests. Together, these results help your care team understand your overall fluid and electrolyte status.
Keeping sodium in a healthy range is essential for normal brain, nerve, and muscle activity. Levels can shift with dehydration, excess water intake, kidney or heart problems, liver disease, and hormone disorders that affect water and salt balance. Gastrointestinal losses such as vomiting or diarrhea can also affect sodium.
Clinicians order this test to evaluate symptoms like fatigue, confusion, headache, muscle cramps, or seizures, to monitor people receiving diuretics or intravenous fluids, and to guide hospital care. Knowing whether sodium is low or high helps tailor treatment, which may include adjusting fluids, reviewing medications, and treating any underlying condition.
Your provider will interpret your sodium result in the context of your age, symptoms, medications, and other labs. Small deviations may not need urgent action, while larger or rapid changes can be more serious and require closer monitoring.
If your result is outside the expected range, follow‑up may include repeating the test, measuring related values such as potassium, chloride, osmolality, glucose, and kidney function, and reviewing your fluid intake and losses. Treatment focuses on the cause and is adjusted carefully to avoid changing sodium too quickly.
Reference intervals vary by laboratory, analyzer, methodology, population, and units. The ranges shown here are for education only. Always interpret your results against the reference interval printed on your own lab report.
Dehydration can raise measured sodium, while excessive water intake or hypotonic fluids can lower it. Recent vomiting, diarrhea, or heavy sweating also shifts sodium.
Diuretics, antidepressants such as SSRIs, carbamazepine or oxcarbazepine, desmopressin, NSAIDs, and some blood pressure medicines can lower sodium. Corticosteroids or mineralocorticoids can raise it.
Drawing blood from or near an IV line that was flushed with saline can falsely raise sodium. Large volumes of hypotonic or hypertonic IV fluids can meaningfully alter results.
Chronic kidney disease, heart failure, cirrhosis, hypothyroidism, adrenal insufficiency, and inappropriate antidiuretic hormone secretion can all disturb sodium balance.
Marked hyperglycemia can lower measured sodium due to water shifts. Severe hyperlipidemia or very high protein levels may cause spurious low values with some analytical methods.
Newborns have different expected sodium ranges than older children and adults. During pregnancy, normal physiology can slightly lower serum sodium due to plasma volume expansion.
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